Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Cyanoacetamide → Milrinone
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Cyanoacetamide | HCID 7898 | — |
| 반응물 | Sodium Hydroxide | HCID 14798 | — |
| 반응물 | 4-Ethoxy-3-(4-pyridyl)-3-buten-2-one | HCID 3021227 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | Milrinone | HCID 4197 | — |
반응 단계
The process according to claim 4 where 2-ethoxy-1-(4-pyridinyl)ethenyl methyl ketone is reacted with cyanoacetamide in the presence of at least a molar equivalent quantity of sodium hydroxide per mole of cyanoacetamide in methanol and the reaction mixture is neutralized to produce 1,2-dihydro-6-methyl-2-oxo-5-(4-pyridinyl)nicotinonitrile.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04469871 |
| 출처 데이터셋 | uspto-grants-1984_09 |
| ORD ID | ord-ca57537861834c5ab7e20e5a6689ba3f |
| 출처 메모 | uspto-grants-1984_09 |