Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1,2-Ethanedithiol → 7-benzyloxycarbonyl-1,4-dithia-7-azaspiro [4.4]nonane-8(S)carboxylic acid, ethyl ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1,2-Ethanedithiol | HCID 10902 | — |
| 반응물 | Ethyl (S)-1-Cbz-4-oxopyrrolidine-2-carboxylate | HCID 14540986 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | 7-benzyloxycarbonyl-1,4-dithia-7-azaspiro [4.4]nonane-8(S)carboxylic acid, ethyl ester | HCID 14540988 | — |
반응 단계
As described in Example 1, react 1-benzyloxycarbonyl-4-keto-(S)-proline, ethyl ester (prepared from the acid by esterification in ethanol) with 1,2-ethane dithiol to obtain 7-benzyloxycarbonyl-1,4-dithia-7-azaspiro[4.4]nonane-8(S)-carboxylic acid, ethyl ester, a yellow oil [α]D26 -21.0° (ethanol).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04470972 |
| 출처 데이터셋 | uspto-grants-1984_09 |
| ORD ID | ord-472e80d5535c4a859bff0ce754ed2f27 |
| 출처 메모 | uspto-grants-1984_09 |