Ammonia → Ethyl 6-amino-8-methoxycarbonyl-4-oxo-10-propyl-4H-pyrano[3,2-g]quinoline-2-carboxylate

HRID 2417931노트

반응식

HRID 2417931 반응식
[CH3:1][O:2][C:3]([C:5]1[CH:14]=[C:13]([NH:15]C(=O)C(Cl)(Cl)Cl)[C:12]2[C:7](=[C:8]([CH2:32][CH2:33][CH3:34])[C:9]3[O:25][C:24]([C:26]([O:28][CH2:29][CH3:30])=[O:27])=[CH:23][C:22](=[O:31])[C:10]=3[CH:11]=2)[N:6]=1)=[O:4].N>S(=O)(=O)(O)O>[NH2:15][C:13]1[C:12]2[C:7](=[C:8]([CH2:32][CH2:33][CH3:34])[C:9]3[O:25][C:24]([C:26]([O:28][CH2:29][CH3:30])=[O:27])=[CH:23][C:22](=[O:31])[C:10]=3[CH:11]=2)[N:6]=[C:5]([C:3]([O:2][CH3:1])=[O:4])[CH:14]=1

참가 물질

4

반응물 2

HCID 222AmmoniaHCID 20233204HCID 20233204, 화합물

생성물 1

HCID 13544003Ethyl 6-amino-8-methoxycarbonyl-4-oxo-10-propyl-4H-pyrano[3,2-g]quinoline-2-carboxylate

시약·촉매·용매 1

HCID 1118Sulfuric Acid용매

실험 절차

The product of step (a) (1.0 g) was dissolved in concentrated sulphuric acid (1 ml) and stirred vigorously for 0.5 hours. The deep red solution was then poured into iced aqueous ammonia solution (100 ml), and the precipitate filtered to give the title compound, 0.5 g, as an orange powder, mp 265°-270° C. (decomposes).

후처리

  1. filtrationthe precipitate filtered

출처 및 근거

ORD 기록
ord-2cccda5063d04274b5dcd9d2158fdfcd
출처 데이터셋
uspto-grants-1984_09
특허 번호
US04471119

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