Isopropylamine → 1-Benzyloxy-4-[6-(1-methylethyl)aminohexyloxy]benzene

HRID 2417986노트

반응식

HRID 2417986 반응식
[CH2:1]([O:8][C:9]1[CH:14]=[CH:13][C:12]([O:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21]Br)=[CH:11][CH:10]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH:23]([NH2:26])([CH3:25])[CH3:24]>>[CH2:1]([O:8][C:9]1[CH:14]=[CH:13][C:12]([O:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][NH:26][CH:23]([CH3:25])[CH3:24])=[CH:11][CH:10]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

참가 물질

3

반응물 2

HCID 6363IsopropylamineHCID 134508831-(Benzyloxy)-4-[(6-bromohexyl)oxy]benzene

생성물 1

HCID 133384811-Benzyloxy-4-[6-(1-methylethyl)aminohexyloxy]benzene

실험 절차

As described in Example 19, 1-benzyloxy-4-(6-bromohexyloxy)benzene was reacted with isopropylamine at 100° (12 hours; 500 psi) to give 1-benzyloxy-4-[6-(1-methylethyl)aminohexyloxy]benzene. The crude oil was crystallized from pentane yielding the purified product, mp 47°-49°.

출처 및 근거

ORD 기록
ord-a12716c74ce84a73acd2f1c10e98f378
출처 데이터셋
uspto-grants-1984_09
특허 번호
US04471116

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