p-Chlorothiophenol → HCID 23693160, 화합물

HRID 2418333노트

반응식

HRID 2418333 반응식
[OH-].[K+:2].[Cl:3][C:4]1[CH:9]=[CH:8][C:7]([SH:10])=[CH:6][CH:5]=1>CO>[Cl:3][C:4]1[CH:9]=[CH:8][C:7]([S-:10])=[CH:6][CH:5]=1.[K+:2]

참가 물질

4

반응물 2

HCID 7815p-ChlorothiophenolHCID 14797Potassium Hydroxide

생성물 1

HCID 23693160HCID 23693160, 화합물

시약·촉매·용매 1

HCID 887Methanol용매2회

실험 절차

To a solution of potassium hydroxide (2.5 g.) in methanol (30 ml.) was dissolved 4-chlorobenzenethiol (6.5 g.), and methanol was distilled off to give potassium 4-chlorobenzenethiolate. To this product were added ethyl 2-(2-nitro-3-chlorophenyl)acetate (10 g.) and dimethylformamide (50 ml.) and stirred for 1.5 hours at 100° C. The reaction mixture was poured into water (300 ml.) and extracted with diethyl ether. The extract was washed with water, dried over magnesium sulfate and then evaporated under reduced pressure. The residue was recrystallized from a mixture of benzene and n-hexane to give yellow needles of the captioned compound (9.9 g.). mp 77° to 79° C.

후처리

  1. distillationwas distilled off

출처 및 근거

ORD 기록
ord-a11aed851c7b4ca3851e97ab0fcdc7b8
출처 데이터셋
uspto-grants-1984_09
특허 번호
US04472433

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