Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Ammonia → 6-(Aminomethyl)pyrimidine-2,4(1H,3H)-dione
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Ammonia | HCID 222 | — |
| 반응물 | 6-(Chloromethyl)-2,4(1H,3H)-pyrimidinedione | HCID 73273 | — |
| 용매 | Ethyl Acetate | HCID 8857 | — |
| 생성물 | 6-(Aminomethyl)pyrimidine-2,4(1H,3H)-dione | HCID 312953 | — |
반응 단계
A mixture of 100 g (0.623 mole) of 6-chloromethylpyrimidine-2,4-dione and 200 ml of anhydrous ammonia was allowed to react overnight in a sealed bomb at about 20° C. The solid residue was slurried in ethyl acetate, separated by filtration, and washed sequentially with water and methanol to provide 6-aminomethylpyrimidine-2,4-dione, m.p. 295°-297° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04473570 |
| 출처 데이터셋 | uspto-grants-1984_09 |
| ORD ID | ord-579362fbdc4e4dc2bed4bbb1e3dcd3be |
| 출처 메모 | uspto-grants-1984_09 |