Benzaldehyde → 3-[(1,3-Benzodithiol-2-ylidene)amino]-5-(phenylmethylene)-2-thioxo-4-thiazolidinone

HRID 2419141

반응식

HRID 2419141 반응식
[S:1]1[C:5]2[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=2[S:3][C:2]1=[N:10][N:11]1[C:15](=[O:16])[CH2:14][S:13][C:12]1=[S:17].[CH:18](=O)[C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1.C([O-])(=O)C.[NH+]1C=CC=CC=1>CCOCC>[S:1]1[C:5]2[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=2[S:3][C:2]1=[N:10][N:11]1[C:15](=[O:16])[C:14](=[CH:18][C:19]2[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=2)[S:13][C:12]1=[S:17]

참가 물질

5

반응물 3

HCID 240BenzaldehydeHCID 124949933-[(1,3-Benzodithiol-2-ylidene)amino]-2-thioxo-4-thiazolidinoneHCID 53401357HOAc pyridine

생성물 1

HCID 539424923-[(1,3-Benzodithiol-2-ylidene)amino]-5-(phenylmethylene)-2-thioxo-4-thiazolidinone

시약·촉매·용매 1

HCID 3283Diethyl Ether용매

반응 조건

온도
120 °C

실험 절차

A mixture of 2.0 g of 3-[(1,3-benzodithiol-2-ylidene)amino]-2-thioxo-4-thiazolidinone (see example 37), benzaldehyde (20 ml, excess) and pyridinium acetate (5 ml) is prepared and heated at 120° C for 3 days under nitrogen with stirring. The mixture is then cooled, diluted with ether and filtered. The residue is washed with water and recrystallized from dimethylformamide to yield 2.2 g of the title compound, melting point 288°-289° C.

후처리

  1. customis prepared
  2. temperatureThe mixture is then cooled
  3. filtrationfiltered
  4. washThe residue is washed with water
  5. customrecrystallized from dimethylformamide

출처 및 근거

ORD 기록
ord-98fb5272e4e3458392daeac260a4d7d7
출처 데이터셋
uspto-grants-1978_08
특허 번호
US04104467

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