Pentabromophenol → o-(Pentabromphenoxymethyl)-benzoic acid-(pentabromophenyl) ester

HRID 2419173노트

반응식

HRID 2419173 반응식
[Br:1][C:2]1[C:7]([OH:8])=[C:6]([Br:9])[C:5]([Br:10])=[C:4]([Br:11])[C:3]=1[Br:12].C1([O-])C=CC=CC=1.[Br:20][C:21]1[C:26]([O:27][C:28](=[O:37])[C:29]2[CH:34]=[CH:33][CH:32]=[CH:31][C:30]=2[CH2:35]Cl)=[C:25]([Br:38])[C:24]([Br:39])=[C:23]([Br:40])[C:22]=1[Br:41]>[OH-].[K+].COCCO>[Br:20][C:21]1[C:26]([O:27][C:28](=[O:37])[C:29]2[CH:34]=[CH:33][CH:32]=[CH:31][C:30]=2[CH2:35][O:8][C:7]2[C:6]([Br:9])=[C:5]([Br:10])[C:4]([Br:11])=[C:3]([Br:12])[C:2]=2[Br:1])=[C:25]([Br:38])[C:24]([Br:39])=[C:23]([Br:40])[C:22]=1[Br:41]

참가 물질

6

반응물 3

HCID 11852PentabromophenolHCID 119047PhenolateHCID 20314961Pentabromophenyl 2-(chloromethyl)benzoate

생성물 1

HCID 53683769o-(Pentabromphenoxymethyl)-benzoic acid-(pentabromophenyl) ester

시약·촉매·용매 2

HCID 80192-Methoxyethanol용매HCID 14797Potassium Hydroxide용매

실험 절차

In a two-liter flask, 5.6 of potassium hydroxide was dissolved at 75° C in 800 ml of methyl glycol; then 48.9 g (= 0.1 mole) of pentabromphenol was stirred in. To this phenolate solution, at 75° C, 64.15 g was added of the o-chloromethylbenzoic acid pentabromophenyl ester, prepared as in Example 9a, and the mixture was heated with stirring to ebullition. It was refluxed for an hour, then cooled, and the solids were isolated and worked up as described in the preceding examples.

후처리

  1. temperaturethe mixture was heated
  2. temperatureIt was refluxed for an hour
  3. temperaturecooled
  4. customthe solids were isolated

출처 및 근거

ORD 기록
ord-5273b953593440aa9322852122727cdb
출처 데이터셋
uspto-grants-1978_08
특허 번호
US04105628

반응 노트

불러오는 중…