2-(Trifluoromethyl)aniline → N-[2-(Trifluoromethyl)phenyl]butanamide

HRID 2419818노트

반응식

HRID 2419818 반응식
[F:1][C:2]([F:11])([F:10])[C:3]1[CH:9]=[CH:8][CH:7]=[CH:6][C:4]=1[NH2:5].[C:12](Cl)(=[O:16])[CH2:13][CH2:14][CH3:15]>>[F:1][C:2]([F:10])([F:11])[C:3]1[CH:9]=[CH:8][CH:7]=[CH:6][C:4]=1[NH:5][C:12](=[O:16])[CH2:13][CH2:14][CH3:15]

참가 물질

3

반응물 2

HCID 69222-(Trifluoromethyl)anilineHCID 8855Butyryl chloride

생성물 1

HCID 3557464N-[2-(Trifluoromethyl)phenyl]butanamide수율 52.8%

실험 절차

Using the procedure of Step A of Example 6, 32.2 g of o-trifluoromethylaniline and 23.44 g of butyryl chloride were reacted to obtain 24.4 g of N-(2-trifluoromethylphenyl)-butanamide melting at 76° C which was used as is for the next step.

후처리

  1. customwere reacted

출처 및 근거

ORD 기록
ord-ca30d8ec23274c73aee119d371e178b7
출처 데이터셋
uspto-grants-1978_08
특허 번호
US04107310

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