2-(1-Methylethylidene)cyclohexanone → HCID 12220944, 화합물

HRID 2419980노트

반응식

HRID 2419980 반응식
[Cl:1]([O-:5])(=[O:4])(=[O:3])=[O:2].[CH:6]1[C:15]2[C:10](=[CH:11][CH:12]=[CH:13][CH:14]=2)[CH2:9][CH2:8][NH+:7]=1.[C:16](=[C:19]1[CH2:24][CH2:23][CH2:22][CH2:21][C:20]1=O)([CH3:18])[CH3:17]>CN(C)C=O.C(O)C>[Cl:1]([O-:5])(=[O:4])(=[O:3])=[O:2].[CH3:18][C:16]1[C:19]2[CH2:24][CH2:23][CH2:22][CH2:21][C:20]=2[N+:7]2[CH2:8][CH2:9][C:10]3[CH:11]=[CH:12][CH:13]=[CH:14][C:15]=3[C:6]=2[CH:17]=1

참가 물질

5

반응물 2

HCID 262522-(1-Methylethylidene)cyclohexanoneHCID 20312280HCID 20312280, 화합물

생성물 1

HCID 12220944HCID 12220944, 화합물

시약·촉매·용매 2

HCID 702Ethanol용매HCID 6228Dimethylformamide용매

실험 절차

3,4-Dihydroisoquinolinium perchlorate (4.6 g) and 2-isopropylidenecyclohexanone (3 g) were dissolved in dimethylforamide (12 ml) and refluxed for 12 hours. The reaction mixture was cooled, diluted with ethanol, and filtered. The product was purified by recrystallization from methanol. Yield 3 g; m.p. 205°.

후처리

  1. temperaturerefluxed for 12 hours
  2. temperatureThe reaction mixture was cooled
  3. filtrationfiltered
  4. customThe product was purified by recrystallization from methanol

출처 및 근거

ORD 기록
ord-27135de797264b0ea899086a2a137f3e
출처 데이터셋
uspto-grants-1978_08
특허 번호
US04108667

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