HCID 678044, 화합물 → Phenylsulphonylacetonitrile

반응식

C(NC1SC=C(C2C=CC=CC=2)C=1C(OCC)=O)(=O)C.C([NH:24][C:25]1SC=C[C:29]=1[S:30]([C:33]1[CH:38]=[CH:37][CH:36]=[CH:35][CH:34]=1)(=[O:32])=[O:31])(=O)C>>[C:33]1([S:30]([CH2:29][C:25]#[N:24])(=[O:31])=[O:32])[CH:34]=[CH:35][CH:36]=[CH:37][CH:38]=1

참가 물질

반응물 2

HCID 678044HCID 678044, 화합물

HCID 20312594HCID 20312594, 화합물

생성물 1

HCID 82077Phenylsulphonylacetonitrile

실험 절차

In place of the 2-acetylamino-3-ethoxycarbonyl-4-phenylthiophene used in Example 4 there is used an equivalent amount of 2-acetylamino-3-phenylsulphonylthiophene (which was obtained by condensing phenylsulphonylacetonitrile with 2:5-dihydroxy-1:4-dithiane in ethanol containing piperidine and subsequently acetylating) whereby 2-amino-3-phenylsulphonyl-5-nitrothiophene (m.pt 155° - 157° C) is obtained.

출처 및 근거

ORD 기록: ord-cc437a27e1804065875a2b53aeac497a
출처 데이터셋: uspto-grants-1978_08
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US04108867

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