Sodium Acetate → 5,7-Dichloro-2,6-dimethylbenzoxazole
반응식
[C:1]([NH:4][C:5]1[CH:10]=[C:9]([Cl:11])[C:8]([CH3:12])=[C:7]([Cl:13])[C:6]=1[OH:14])(=O)[CH3:2].C([O-])(=O)C.[Na+]>>[CH3:2][C:1]1[O:14][C:6]2[C:7]([Cl:13])=[C:8]([CH3:12])[C:9]([Cl:11])=[CH:10][C:5]=2[N:4]=1참가 물질
3
실험 절차
A mixture of 79 g. of 2-acetylamino-5-methyl-4,6-di-chloro-phenol and 3.6 g. of anhydrous sodium acetate was heated at 180° C. for some minutes. The liquid obtained was distilled under vacuum, collecting the fraction passed from 140° C. to 145° C. at 1.2 mm. Hg. The distilled oil became a mass of crystals which was purified by crystallization from ligroin. 36 g. of pure base were obtained. M.P. = 80°-82° C.
후처리
- additionA mixture of 79 g
- customThe liquid obtained
- distillationwas distilled under vacuum
- customcollecting the fraction
- custompassed from 140° C. to 145° C. at 1.2 mm. Hg
- customwas purified by crystallization from ligroin
- customof pure base were obtained
출처 및 근거
- ORD 기록
- ord-40c5016a1f734a95816ab8afa5e77933
- 출처 데이터셋
- uspto-grants-1978_08
- 특허 번호
- US04110116
반응 노트
불러오는 중…