2,7-Dimethyl-1,3,7-octatriene → Tetrahydronaphthoquinone Isoprene

HRID 2420270노트

반응식

HRID 2420270 반응식
[C:1]1(=[O:12])[C:10]2[CH:5]([CH2:6][CH:7]=[CH:8][CH:9]=2)[C:4](=[O:11])[CH2:3][CH2:2]1.[CH3:13][C:14]([CH:16]=[CH:17]CCC(C)=C)=[CH2:15]>C1CCCCC1>[C:4]1(=[O:11])[C:5]2[CH:10]([CH2:9][CH:8]=[CH:7][CH:6]=2)[C:1](=[O:12])[CH2:2][CH2:3]1.[CH2:17]=[CH:16][C:14](=[CH2:13])[CH3:15]

참가 물질

4

반응물 2

HCID 5570852,7-Dimethyl-1,3,7-octatrieneHCID 17958094Tetrahydronaphthoquinone

생성물 1

HCID 86735968Tetrahydronaphthoquinone Isoprene수율 105.5%

시약·촉매·용매 1

HCID 8078Cyclohexane용매

실험 절차

A solution of 101 g (0.623 mole) of tetrahydronaphthoquinone and 110 g (0.81 mole) of 2,7-dimethyl-1,3,7-octatriene in 300 ml cyclohexane was refluxed for 18 hours. After removal of 200 ml solvent, 300 ml of hexane were added. The mixture was then warmed, stirred with powdered charcoal, and filtered. On cooling, 151.3 g of crude product were obtained (81.5% yield). A 3 g analytical sample, after recrystallization from 20 ml hexane, had a mp of 87.5° to 88° C.

후처리

  1. customAfter removal of 200 ml solvent, 300 ml of hexane
  2. additionwere added
  3. temperatureThe mixture was then warmed
  4. filtrationfiltered
  5. temperatureOn cooling

출처 및 근거

ORD 기록
ord-14fdc9fc52034e8b9284bdf7c524883b
출처 데이터셋
uspto-grants-1978_08
특허 번호
US04110353

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