참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | N-bromobutanimide | HCID 67184 | — |
| 반응물 | Ethyl 6-oxo-2-(pentafluoroethyl)-1,4,5,6-tetrahydropyridine-3-carboxylate | HCID 86611248 | — |
| 용매 | Carbon Tetrachloride | HCID 5943 | — |
| 생성물 | Ethyl 6-oxo-2-(pentafluoroethyl)-1,6-dihydropyridine-3-carboxylate | HCID 86611249 | 43.8% |
반응 단계
A suspension of ethyl 6-oxo-2-(pentafluoroethyl)-1,4,5,6-tetrahydropyridine-3-carboxylate (0.690 g) and N-bromosuccinimide (0.427 g) in carbon tetrachloride (5 mL) was heated at 80° C. for 20 h. The reaction mixture was concentrated in vacuo and subjected to flash column chromatography (eluent 1:3 ethyl acetate/isohexane) to yield a colourless solid (0.30 g).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US07956070B2 |
|---|
| 출처 데이터셋 | uspto-grants-2011_06 |
|---|
| ORD ID | ord-885a408ad58b46549dc94731e4f37375 |
|---|
| 출처 메모 | uspto-grants-2011_06 |
|---|
