Tert-Butylamine → HCID 67214351, 화합물

반응식

[I:1][C:2]1[CH:3]=[N:4][C:5]2[C:10]([CH:11]=1)=[CH:9][C:8]([O:12][CH:13]([S:17][CH3:18])[C:14]([OH:16])=O)=[CH:7][C:6]=2[CH3:19].[C:20]([NH2:24])([CH3:23])([CH3:22])[CH3:21]>>[C:20]([NH:24][C:14](=[O:16])[CH:13]([O:12][C:8]1[CH:9]=[C:10]2[C:5](=[C:6]([CH3:19])[CH:7]=1)[N:4]=[CH:3][C:2]([I:1])=[CH:11]2)[S:17][CH3:18])([CH3:23])([CH3:22])[CH3:21]

참가 물질

반응물 2

HCID 6385Tert-Butylamine

HCID 67213779HCID 67213779, 화합물

생성물 1

HCID 67214351HCID 67214351, 화합물

실험 절차

In a similar procedure to Stage 2 of Example 1, (3-iodo-8-methyl-quinolin-6-yloxy)-methylsulfanyl-acetic acid was condensed with t-butylamine to give N-tert-Butyl-2-(3-iodo-8-methyl-quinolin-6-yloxy)-2-methylsulfanyl-acetamide as a white solid ([M+1]+ 445).

출처 및 근거

ORD 기록: ord-9f70b8803d524cc299b3622cec88d6f4
출처 데이터셋: uspto-grants-2011_06
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07956188B2

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