Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Anthranilic Acid → 2-(2-Methoxy-4-{3-[(3S)-3-methylpiperidin-1-yl]propoxy}phenyl)-3-methylquinazolin-4(3H)-one
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Anthranilic Acid | HCID 227 | — |
| 반응물 | Methylamine | HCID 6329 | — |
| 반응물 | 1-Bromo-3-chloropropane | HCID 8006 | — |
| 반응물 | 4-Hydroxy-2-Methoxybenzaldehyde | HCID 519541 | — |
| 반응물 | (S)-3-Methylpiperidine | HCID 641100 | — |
| 반응물 | (R)-Mandelate | HCID 5460269 | — |
| 생성물 | 2-(2-Methoxy-4-{3-[(3S)-3-methylpiperidin-1-yl]propoxy}phenyl)-3-methylquinazolin-4(3H)-one | HCID 11524620 | — |
반응 단계
The entitled compound was obtained according to the method of Example 1 but starting from anthranilic acid, methylamine, 4-hydroxy-2-methoxybenzaldehyde, 1-chloro-3-bromopropane and (3S)-3-methylpiperidine.(R)-mandelate.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07960394B2 |
| 출처 데이터셋 | uspto-grants-2011_06 |
| ORD ID | ord-d9c3f9ea6a474542981abb432eb5cb2e |
| 출처 메모 | uspto-grants-2011_06 |