Methylamine → 4(3h)-Quinazolinone,2-[6-[(1-cyclobutyl-4-piperidinyl)oxy]-3-pyridinyl]-8-methoxy-3-methyl-

HRID 2422599노트

반응식

HRID 2422599 반응식
[NH2:1][C:2]1[C:10]([O:11][CH3:12])=[CH:9][CH:8]=[CH:7][C:3]=1[C:4]([OH:6])=O.[CH3:13][NH2:14].[CH:15]1([N:19]2[CH2:24][CH2:23][CH:22]([O:25][C:26]3[CH:33]=[CH:32][C:29]([CH:30]=O)=[CH:28][N:27]=3)[CH2:21][CH2:20]2)[CH2:18][CH2:17][CH2:16]1>>[CH:15]1([N:19]2[CH2:24][CH2:23][CH:22]([O:25][C:26]3[N:27]=[CH:28][C:29]([C:30]4[N:14]([CH3:13])[C:4](=[O:6])[C:3]5[C:2](=[C:10]([O:11][CH3:12])[CH:9]=[CH:8][CH:7]=5)[N:1]=4)=[CH:32][CH:33]=3)[CH2:21][CH2:20]2)[CH2:18][CH2:17][CH2:16]1

참가 물질

4

반응물 3

HCID 6329MethylamineHCID 2557202-Amino-3-methoxybenzoic acidHCID 866244636-[(1-Cyclobutylpiperidin-4-yl)oxy]nicotinaldehyde

생성물 1

HCID 116546844(3h)-Quinazolinone,2-[6-[(1-cyclobutyl-4-piperidinyl)oxy]-3-pyridinyl]-8-methoxy-3-methyl-

실험 절차

The entitled compound was obtained according to the method of Example 15 but starting from 2-amino-3-methoxybenzoic acid, methylamine and 6-[(1-cyclobutylpiperidin-4-yl)oxy]nicotinaldehyde.

후처리

  1. customThe entitled compound was obtained

출처 및 근거

ORD 기록
ord-c9d7854d37d04d6ba0cc9c1b5aaf5bb6
출처 데이터셋
uspto-grants-2011_06
특허 번호
US07960394B2

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