[4-(2-Diisopropylaminoethoxy)phenyl][5-methoxy-2-(6-methoxynaphthalen-2-yl)phenyl]methanone → 6-{2-[4-(2-Diisopropylaminoethoxy)benzyl]-4-hydroxyphenyl}naphthalen-2-ol
반응식
[CH:1]([N:4]([CH:36]([CH3:38])[CH3:37])[CH2:5][CH2:6][O:7][C:8]1[CH:13]=[CH:12][C:11]([C:14]([C:16]2[CH:21]=[C:20]([O:22]C)[CH:19]=[CH:18][C:17]=2[C:24]2[CH:33]=[CH:32][C:31]3[C:26](=[CH:27][CH:28]=[C:29]([O:34]C)[CH:30]=3)[CH:25]=2)=O)=[CH:10][CH:9]=1)([CH3:3])[CH3:2].C(N(C(C)C)CCOC1C=CC(CC2C=C(OC)C=CC=2C2C=CC3C(=CC=C(OC)C=3)C=2)=CC=1)(C)C>>[CH:36]([N:4]([CH:1]([CH3:3])[CH3:2])[CH2:5][CH2:6][O:7][C:8]1[CH:13]=[CH:12][C:11]([CH2:14][C:16]2[CH:21]=[C:20]([OH:22])[CH:19]=[CH:18][C:17]=2[C:24]2[CH:25]=[C:26]3[C:31](=[CH:32][CH:33]=2)[CH:30]=[C:29]([OH:34])[CH:28]=[CH:27]3)=[CH:10][CH:9]=1)([CH3:37])[CH3:38]참가 물질
3
실험 절차
Synthesized from [4-(2-diisopropylaminoethoxy)phenyl][5-methoxy-2-(6-methoxynaphthalen-2-yl)phenyl]methanone according to an analogous synthetic method to Example 337 described below, diisopropyl{2-{4-[5-methoxy-2-(6-methoxynaphthalen-2-yl)benzyl]phenoxy}ethyl}amine (398 mg) was used according to an analogous synthetic method to Example 111 described below to provide the title compound (80 mg).