Acetone → 6-(2-Isopropylamino-4-methoxyphenyl)-5,6,7,8-tetrahydronaphthalen-2-ol

HRID 2423685노트

반응식

HRID 2423685 반응식
[NH2:1][C:2]1[CH:7]=[C:6]([O:8][CH3:9])[CH:5]=[CH:4][C:3]=1[CH:10]1[CH2:19][CH2:18][C:17]2[CH:16]=[C:15]([OH:20])[CH:14]=[CH:13][C:12]=2[CH2:11]1.[CH3:21][C:22]([CH3:24])=O>>[CH:22]([NH:1][C:2]1[CH:7]=[C:6]([O:8][CH3:9])[CH:5]=[CH:4][C:3]=1[CH:10]1[CH2:19][CH2:18][C:17]2[CH:16]=[C:15]([OH:20])[CH:14]=[CH:13][C:12]=2[CH2:11]1)([CH3:24])[CH3:21]

참가 물질

3

반응물 2

HCID 180AcetoneHCID 230873286-(2-Amino-4-methoxyphenyl)-5,6,7,8-tetrahydronaphthalen-2-ol

생성물 1

HCID 230874436-(2-Isopropylamino-4-methoxyphenyl)-5,6,7,8-tetrahydronaphthalen-2-ol

실험 절차

Synthesized from 6-(2-amino-4-methoxyphenyl)-5,6,7,8-tetrahydronaphthalen-2-ol (1.4 g) and acetone (1.5 ml) according to an analogous synthetic method to Example 38, the title compound (1.2 g) was obtained.

출처 및 근거

ORD 기록
ord-19d433b025cd48469e317fb6a62aacd9
출처 데이터셋
uspto-grants-2011_06
특허 번호
US07960412B2

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