1-Bromo-3,4-(methylenedioxy)benzene → 5-(6-Benzyloxy-3,4-dihydronaphthalen-2-yl)-6-nitrobenzo[1,3]dioxole

HRID 2423691노트

반응식

HRID 2423691 반응식
BrC1C=CC2OCOC=2C=1.Br[C:12]1[C:20]([N+:21]([O-:23])=[O:22])=[CH:19][C:15]2[O:16][CH2:17][O:18][C:14]=2[CH:13]=1.[CH2:24]([O:31][C:32]1[CH:41]=[C:40]2[C:35]([CH:36]=[C:37](Br)[CH2:38][CH2:39]2)=[CH:34][CH:33]=1)[C:25]1[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=1>>[CH2:24]([O:31][C:32]1[CH:41]=[C:40]2[C:35](=[CH:34][CH:33]=1)[CH:36]=[C:37]([C:12]1[C:20]([N+:21]([O-:23])=[O:22])=[CH:19][C:15]3[O:16][CH2:17][O:18][C:14]=3[CH:13]=1)[CH2:38][CH2:39]2)[C:25]1[CH:26]=[CH:27][CH:28]=[CH:29][CH:30]=1

참가 물질

4

반응물 3

HCID 758311-Bromo-3,4-(methylenedioxy)benzeneHCID 15197565-Bromo-6-nitro-1,3-benzodioxoleHCID 230874203-Bromo-1,2-dihydro-7-(phenylmethoxy)naphthalene

생성물 1

HCID 666270645-(6-Benzyloxy-3,4-dihydronaphthalen-2-yl)-6-nitrobenzo[1,3]dioxole수율 10.9%

실험 절차

Synthesized from 4-bromo-1,2-(methylenedioxy)benzene according to an analogous synthetic method to Preparation Example 108, 5-bromo-6-nitrobenzo[1,3]dioxole (9.4 g) and 7-benzyloxy-3-bromo-1,2-dihydronaphthalene (6.0 g) were used according to an analogous synthetic method to Preparation Example 107 to provide the title compound (834 mg).

후처리

  1. customwere used according to an analogous synthetic method to Preparation Example 107

출처 및 근거

ORD 기록
ord-242fb9f91ddf43f28081a8c584d90d66
출처 데이터셋
uspto-grants-2011_06
특허 번호
US07960412B2

반응 노트

불러오는 중…