1-Piperidinecarbonyl chloride → HCID 71105119, 화합물

HRID 242390

반응식

HRID 242390 반응식
[OH:1][CH2:2][C:3]1[N:4]=[C:5]([C:16](=[O:18])[CH3:17])[N:6]([CH2:8][O:9][CH2:10][CH2:11][Si:12]([CH3:15])([CH3:14])[CH3:13])[CH:7]=1.[N:19]1([C:25](Cl)=[O:26])[CH2:24][CH2:23][CH2:22][CH2:21][CH2:20]1>>[C:16]([C:5]1[N:6]([CH2:8][O:9][CH2:10][CH2:11][Si:12]([CH3:14])([CH3:13])[CH3:15])[CH:7]=[C:3]([CH2:2][O:1][C:25]([N:19]2[CH2:24][CH2:23][CH2:22][CH2:21][CH2:20]2)=[O:26])[N:4]=1)(=[O:18])[CH3:17]

참가 물질

3

반응물 2

HCID 2420851-Piperidinecarbonyl chlorideHCID 71086972HCID 71086972, 화합물

생성물 1

HCID 71105119HCID 71105119, 화합물

실험 절차

In analogy to Step (4) of Example 48, but using 1-(4-hydroxymethyl-1-(2-trimethylsilylethoxymethyl)-1H-imidazol-2-yl)ethanone (1.50 g) and piperidine-1-ylcarbonyl chloride (0.763 mL), the title compound (1.93 g) was afforded.

출처 및 근거

ORD 기록
ord-d59109acb5604b629cf7ea4da7541296
출처 데이터셋
uspto-grants-2014_02
특허 번호
US08653126B2

연결된 노트

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