Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Acetate → Octreotide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Acetate | HCID 175 | — |
| 반응물 | Citrate | HCID 31348 | — |
| 반응물 | Octreotide phytate | HCID 86603142 | — |
| 생성물 | Octreotide | HCID 448601 | — |
반응 단계
Poly(DL-lactide-co-glycolide) (PLGA) having a 50/50 ratio of lactide to glycolide (DL2.5A from Alkermes) was dissolved in N-methyl-2-pyrrolidone (NMP), or methoxypolyethylene glycohol (mPEG) to give a 40% solution by weight. The injectable polymer solutions were prepared by dispersing octreotide phytate or acetate or citrate. The mixture was thoroughly mixed until a uniform suspension or solution was obtained. Injectable formulations were prepared as shown below.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07964219B2 |
| 출처 데이터셋 | uspto-grants-2011_06 |
| ORD ID | ord-79a3749a68ec4e15bafae9d5be21d4d9 |
| 출처 메모 | uspto-grants-2011_06 |