Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
(R)-beta-aminophenethyl alcohol → (R)-N-(2-hydroxy-1-phenylethyl)-5-methyl-3-(2,4,5-trifluorophenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine-1-carboxamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | (R)-beta-aminophenethyl alcohol | HCID 2724025 | — |
| 반응물 | (S)-N-(3,3-dimethyl-1-(methylamino)-1-oxobutan-2-yl)-5-methyl-3-(2,4,5-trifluorophenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine-1-carboxamide | HCID 46863441 | — |
| 생성물 | (R)-N-(2-hydroxy-1-phenylethyl)-5-methyl-3-(2,4,5-trifluorophenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine-1-carboxamide | HCID 46861921 | — |
반응 단계
Compound 70 was prepared according to the procedure described for the synthesis of compound 37 by replacing tert-leucine methylamide with (R)-2-amino-2-phenylethanol. LCMS (+ESI) m/z=431.2 [M+H]+.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08653127B2 |
| 출처 데이터셋 | uspto-grants-2014_02 |
| ORD ID | ord-eeb770535cec4d84a4178574c37732ef |
| 출처 메모 | uspto-grants-2014_02 |