5-amino-1-(2-methoxyphenyl)-1H-pyrazole-4-carboxamide → 5-amino-1-cyclopentyl-3-methyl-1H-pyrazole-4-carboxamide

HRID 2424766노트

반응식

HRID 2424766 반응식
[NH2:1][C:2]1[N:6]([C:7]2[CH:12]=[CH:11][CH:10]=[CH:9]C=2OC)[N:5]=[CH:4][C:3]=1[C:15]([NH2:17])=[O:16].N[C:19]1N(C2CCCC2)N=C(C)C=1C#N>>[NH2:1][C:2]1[N:6]([CH:7]2[CH2:12][CH2:11][CH2:10][CH2:9]2)[N:5]=[C:4]([CH3:19])[C:3]=1[C:15]([NH2:17])=[O:16]

참가 물질

3

반응물 2

HCID 121517035-amino-1-(2-methoxyphenyl)-1H-pyrazole-4-carboxamideHCID 15428981HCID 15428981, 화합물

생성물 1

HCID 154289805-amino-1-cyclopentyl-3-methyl-1H-pyrazole-4-carboxamide

실험 절차

Following the procedure for the preparation of 5-amino-1-(2-methoxyphenyl)-1H-pyrazole-4-carboxamide but substituting 5-amino-1-cyclopentyl-3-methyl-1H-pyrazole-4-carbonitrile provided the title compound. 1H NMR (300 MHz, CDCl3): δ 5.39 (br, 2H), 5.32 (br, 2H), 4.26 (m, 1H), 2.38 (s, 3H), 2.04 (m, 4H), 1.9 (m, 2H), 1.66 (m, 2H).

출처 및 근거

ORD 기록
ord-e79fbc170a924f45ba9b13e6019a2d50
출처 데이터셋
uspto-grants-2011_06
특허 번호
US07964607B2

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