2,2,2-Trifluoroethylhydrazine → 5-Amino-1-(2,2,2-trifluoroethyl)-1H-pyrazole-4-carbonitrile

HRID 2424786노트

반응식

HRID 2424786 반응식
[NH2:1][C:2]1N(C2C=CC=CC=2OC)[N:5]=[CH:4][C:3]=1[C:15]#N.[F:17][C:18]([F:23])([F:22])[CH2:19][NH:20][NH2:21]>>[NH2:5][C:4]1[N:20]([CH2:19][C:18]([F:23])([F:22])[F:17])[N:21]=[CH:15][C:3]=1[C:2]#[N:1]

참가 물질

3

반응물 2

HCID 787402,2,2-TrifluoroethylhydrazineHCID 121505605-amino-1-(2-methoxyphenyl)-1H-pyrazole-4-carbonitrile

생성물 1

HCID 534183335-Amino-1-(2,2,2-trifluoroethyl)-1H-pyrazole-4-carbonitrile

실험 절차

Following the procedure for the preparation of 5-amino-1-(2-methoxyphenyl)-1H-pyrazole-4-carbonitrile but substituting 1-(2,2,2-trifluoroethyl)hydrazine provided the title compound. 400 MHz 1H NMR (CDCl3) δ 7.60 (s, 1H), 4.59 (m, 2H), 4.40 (brs, 2H).

출처 및 근거

ORD 기록
ord-dc4990f665254fc7bff489a3e58334c6
출처 데이터셋
uspto-grants-2011_06
특허 번호
US07964607B2

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