1,2-Dibromoethane → Ethyl 1-(pyridin-3-yl)cyclopropane-1-carboxylate

HRID 2424927노트

반응식

HRID 2424927 반응식
[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([CH2:7][C:8]([O:10][CH2:11][CH3:12])=[O:9])[CH:2]=1.Br[CH2:14][CH2:15]Br>>[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([C:7]2([C:8]([O:10][CH2:11][CH3:12])=[O:9])[CH2:15][CH2:14]2)[CH:2]=1

참가 물질

3

반응물 2

HCID 78391,2-DibromoethaneHCID 96490Ethyl 3-pyridylacetate

생성물 1

HCID 21054369Ethyl 1-(pyridin-3-yl)cyclopropane-1-carboxylate

실험 절차

Prepared in a similar manner to that described above by reacting ethyl 2-pyridin-3-ylacetate with 1,2-dibromoethane to give ethyl 1-pyridin-3-ylcyclopropane-1-carboxylate which was then hydrogenated to give the desired compound as a brown oil (quantitative reaction).

후처리

  1. customPrepared in a similar manner to that

출처 및 근거

ORD 기록
ord-05c0d4fc55d9412d928d375df8b38f21
출처 데이터셋
uspto-grants-2011_06
특허 번호
US07964618B2

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