Hippuric Acid → Rac-n-({[phenyl-(3-trifluoromethyl-phenyl)-methyl]-carbamoyl}-methyl)-benzamide

HRID 2425199

반응식

HRID 2425199 반응식
[C:1]1([CH:7]([NH2:18])[C:8]2[CH:13]=[CH:12][CH:11]=[C:10]([C:14]([F:17])([F:16])[F:15])[CH:9]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[C:19](O)(=[O:30])[CH2:20][NH:21][C:22]([C:24]1[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=1)=[O:23]>>[C:1]1([CH:7]([NH:18][C:19]([CH2:20][NH:21][C:22](=[O:23])[C:24]2[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=2)=[O:30])[C:8]2[CH:13]=[CH:12][CH:11]=[C:10]([C:14]([F:16])([F:17])[F:15])[CH:9]=2)[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

참가 물질

3

반응물 2

HCID 464Hippuric AcidHCID 21528802Phenyl(3-(trifluoromethyl)phenyl)methanamine

생성물 1

HCID 24899994Rac-n-({[phenyl-(3-trifluoromethyl-phenyl)-methyl]-carbamoyl}-methyl)-benzamide

실험 절차

Prepared in analogy to example 1.1 from rac-C-phenyl-C-(3-trifluoromethyl-phenyl)-methylamine (CA [70428-92-1]) and hippuric acid.

출처 및 근거

ORD 기록
ord-e3b808349a5d481a81f417ae092dac09
출처 데이터셋
uspto-grants-2011_06
특허 번호
US07964645B2

연결된 노트

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