4-Fluorohippuric acid → N-(2-(bis(3-fluorophenyl)methylamino)-2-oxoethyl)-4-fluorobenzamide

HRID 2425239노트

반응식

HRID 2425239 반응식
[F:1][C:2]1[CH:14]=[CH:13][C:5]([C:6](=[O:12])[NH:7][CH2:8][C:9]([OH:11])=O)=[CH:4][CH:3]=1.[F:15][C:16]1[CH:17]=[C:18]([CH:22]([NH2:30])[C:23]2[CH:28]=[CH:27][CH:26]=[C:25]([F:29])[CH:24]=2)[CH:19]=[CH:20][CH:21]=1>>[F:15][C:16]1[CH:17]=[C:18]([CH:22]([NH:30][C:9]([CH2:8][NH:7][C:6](=[O:12])[C:5]2[CH:4]=[CH:3][C:2]([F:1])=[CH:14][CH:13]=2)=[O:11])[C:23]2[CH:28]=[CH:27][CH:26]=[C:25]([F:29])[CH:24]=2)[CH:19]=[CH:20][CH:21]=1

참가 물질

3

반응물 2

HCID 6993414-Fluorohippuric acidHCID 22506791Bis(3-fluorophenyl)methanamine

생성물 1

HCID 24743795N-(2-(bis(3-fluorophenyl)methylamino)-2-oxoethyl)-4-fluorobenzamide

실험 절차

Prepared in analogy to example 1.1 from 4-fluoro-hippuric acid (CA [366-79-0]) and C,C-bis-(3-fluoro-phenyl)-methylamine (CA [261925-16-0]).

출처 및 근거

ORD 기록
ord-acaec760223d4ff6ab31cb61294b4c0b
출처 데이터셋
uspto-grants-2011_06
특허 번호
US07964645B2

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