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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 2425640생성일: 2026년 10월 26일

1-Acetylpiperazine → 1-{4-[(4S,5R)-2-(4-tert-Butyl-2-ethoxy-phenyl)-4,5-bis-(4-chloro-phenyl)-4,5-dihydro-imidazole-1-carbonyl]-piperazin-1-yl}-ethanone hydrochloride

https://huagongshe.com/reaction/2425640

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참여 물질

역할이름HCID투입량
반응물1-AcetylpiperazineHCID 83795—
반응물(4S,5R)-2-(4-tert-butyl-2-ethoxy-phenyl)-4,5-bis-(4-chloro-phenyl)-4,5-dihydro-imidazole-1-carbonyl chlorideHCID 57732375—
생성물1-{4-[(4S,5R)-2-(4-tert-Butyl-2-ethoxy-phenyl)-4,5-bis-(4-chloro-phenyl)-4,5-dihydro-imidazole-1-carbonyl]-piperazin-1-yl}-ethanone hydrochlorideHCID 67013728—

반응 단계

1-{4-[(4S,5R)-2-(4-tert-Butyl-2-ethoxy-phenyl)-4,5-bis-(4-chloro-phenyl)-4,5-dihydro-imidazole-1-carbonyl]-piperazin-1-yl}-ethanone hydrochloride was prepared from (4S,5R)-2-(4-tert-butyl-2-ethoxy-phenyl)-4,5-bis-(4-chloro-phenyl)-4,5-dihydro-imidazole-1-carbonyl chloride (example 11) and 1-acetyl-piperazine in an analogous manner as described in example 25. LR-MS: 621.4 [(M+H)+]

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US07964724B2
출처 데이터셋uspto-grants-2011_06
ORD IDord-d0f3d5ef15c14122b1c72c976686879c
출처 메모uspto-grants-2011_06