Benzoyl Peroxide → HCID 67252371, 화합물
반응식
[CH3:1][O:2][C:3](=[O:13])[C:4]1[C:9]([CH3:10])=[CH:8][C:7]([F:11])=[CH:6][C:5]=1[I:12].[Br:14]NC(=O)CCC(N)=O.C(OOC(=O)C1C=CC=CC=1)(=O)C1C=CC=CC=1>C(Cl)(Cl)(Cl)Cl>[CH3:1][O:2][C:3](=[O:13])[C:4]1[C:5]([I:12])=[CH:6][C:7]([F:11])=[CH:8][C:9]=1[CH2:10][Br:14]참가 물질
5
실험 절차
A mixture of 4-fluoro-2-iodo-6-methyl-benzoic acid methyl ester (1.14 g, 3.74 mmol), N-bromosuccinamide (0.796 g, 4.5 mmol), and benzoyl peroxide (0.024 g, 0.146 mmol) in carbon tetrachloride (50 mL) was heated at reflux until majority of ester was consumed (as analyzed by GC/MS). The resulting mixture was filtered, the filtrate was concentrated to afford 2-bromomethyl-4-fluoro-6-iodo-benzoic acid methyl ester. The material was used without further purification
후처리
- temperaturewas heated
- customwas consumed (as analyzed by GC/MS)
- filtrationThe resulting mixture was filtered
- concentrationthe filtrate was concentrated
출처 및 근거
- ORD 기록
- ord-491d573530a54bdeac5ccf6a96f819b0
- 출처 데이터셋
- uspto-grants-2011_06
- 특허 번호
- US07968570B2
반응 노트
불러오는 중…