Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Methyl 4-(chlorocarbonyl)benzoate → 5-(4-Methoxycarbonylbenzamido)-2-oxindole
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Methyl 4-(chlorocarbonyl)benzoate | HCID 81850 | — |
| 반응물 | 5-Amino-2-oxindole | HCID 2773213 | — |
| 용매 | Pyridine | HCID 1049 | — |
| 생성물 | 5-(4-Methoxycarbonylbenzamido)-2-oxindole | HCID 23289962 | 81% |
반응 단계
A mixture of 82.0 mg 5-amino-2-oxindole and 131.0 mg 4-methoxycarbonylbenzoyl chloride in pyridine was stirred at room temperature for 3 hr and poured into ice water. The precipitate was filtered, washed with water and dried in a vacuum oven to give 138.0 mg of 5-(4-methoxycarbonylbenzamido)-2oxindole (81% yield).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06855730B2 |
| 출처 데이터셋 | uspto-grants-2005_02 |
| ORD ID | ord-1c489b6e3bdf42119d09d797f8064076 |
| 출처 메모 | uspto-grants-2005_02 |