4-Nitrobenzoic Acid → N-(4-Methylphenyl)-4-nitrobenzamide

반응식

[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([CH3:8])=[CH:4][CH:3]=1.[N+:9]([C:12]1[CH:20]=[CH:19][C:15]([C:16]([OH:18])=O)=[CH:14][CH:13]=1)([O-:11])=[O:10]>>[N+:9]([C:12]1[CH:13]=[CH:14][C:15]([C:16]([NH:1][C:2]2[CH:7]=[CH:6][C:5]([CH3:8])=[CH:4][CH:3]=2)=[O:18])=[CH:19][CH:20]=1)([O-:11])=[O:10]

참가 물질

반응물 2

HCID 61084-Nitrobenzoic Acid

HCID 7813p-Toluidine

생성물 1

HCID 591812N-(4-Methylphenyl)-4-nitrobenzamide수율 99.6%

실험 절차

Using p-toluidine (1.19 g, 11.0 mmol) and 4-nitrobenzoic acid (1.77 g, 10.5 mmol), the procedure of Reference Example 16 was repeated to obtain 2.68 g (99.6%) of the title compound in the form of light yellow needle crystals.

출처 및 근거

ORD 기록: ord-225d5fd599ed478295e732ac8190f2ec
출처 데이터셋: uspto-grants-1998_03
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US05728835

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