Tert-butyl octahydropyrrolo(3,4-c)pyrrole-2-carboxylate → 2-(4,6-Dimethoxy-pyrimidin-2-yl)-octahydro-pyrrolo[3,4-c]pyrrole

HRID 243847

반응식

HRID 243847 반응식
Cl[C:2]1[N:7]=[C:6]([O:8][CH3:9])[CH:5]=[C:4]([O:10][CH3:11])[N:3]=1.C(OC([N:19]1[CH2:26][CH:25]2[CH:21]([CH2:22][NH:23][CH2:24]2)[CH2:20]1)=O)(C)(C)C>>[CH3:11][O:10][C:4]1[CH:5]=[C:6]([O:8][CH3:9])[N:7]=[C:2]([N:19]2[CH2:26][CH:25]3[CH:21]([CH2:22][NH:23][CH2:24]3)[CH2:20]2)[N:3]=1

참가 물질

3

반응물 2

HCID 4142526Tert-butyl octahydropyrrolo(3,4-c)pyrrole-2-carboxylateHCID 51523232-Chloro-4,6-dimethoxypyrimidine

생성물 1

HCID 671164912-(4,6-Dimethoxy-pyrimidin-2-yl)-octahydro-pyrrolo[3,4-c]pyrrole

실험 절차

The title compound was prepared in a manner analogous to Intermediate 23 utilizing 2-chloro-4,6-dimethoxypyrimidine and hexahydro-pyrrolo[3,4-c]pyrrole-2-carboxylic acid tert-butyl ester as starting materials.

출처 및 근거

ORD 기록
ord-72a202a5017648db8fbf1a008883f11c
출처 데이터셋
uspto-grants-2014_02
특허 번호
US08653263B2

연결된 노트

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