Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Chloro-6-methylnicotinic acid → 3-[1,2,3]Triazol-2-yl-pyridine-2-carboxylic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Chloro-6-methylnicotinic acid | HCID 121724 | — |
| 반응물 | 3-Bromopyridine-2-carboxylic Acid | HCID 2050129 | — |
| 반응물 | 6-Methyl-2-[1,2,3]triazol-2-yl-nicotinic acid | HCID 67086855 | — |
| 생성물 | 3-[1,2,3]Triazol-2-yl-pyridine-2-carboxylic acid | HCID 66742288 | — |
반응 단계
The title compound was prepared in a manner analogous to Intermediate 70 substituting 3-bromo-2-pyridinecarboxylic acid for 2-chloro-6-methylnicotinic acid. MS (ESI): mass calculated for C8H6N4O2, 190.10; m/z found 191.1 [M+H]+. 1H NMR (400 MHz, CDCl3): 8.77 (d, J=4.3 Hz, 1H), 8.26 (dt, J=6.5, 3.3 Hz, 1H), 7.88 (s, 2H), 7.65 (dd, J=8.2, 4.7 Hz, 1H).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08653263B2 |
| 출처 데이터셋 | uspto-grants-2014_02 |
| ORD ID | ord-118dfbd8519d4f50923d0036be63e290 |
| 출처 메모 | uspto-grants-2014_02 |