Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Chloro-6-methylnicotinic acid → 5-[1,2,3]Triazol-2-yl-benzo[1,3]dioxole-4-carboxylic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Chloro-6-methylnicotinic acid | HCID 121724 | — |
| 반응물 | 5-Bromobenzo(1,3)dioxole-4-carboxylic acid | HCID 12514106 | — |
| 반응물 | 6-Methyl-2-[1,2,3]triazol-2-yl-nicotinic acid | HCID 67086855 | — |
| 생성물 | 5-[1,2,3]Triazol-2-yl-benzo[1,3]dioxole-4-carboxylic acid | HCID 67116281 | — |
반응 단계
The title compound was prepared in a manner analogous to Intermediate 70 substituting 5-bromobenzo[1,3]dioxole-4-carboxylic acid for 2-chloro-6-methylnicotinic acid. MS (ESI): mass calculated for C10H7N3O4, 233.18; m/z found 234.3 [M+H]+. 1H NMR (400 MHz, CD3OD): 7.85 (s, 2H), 7.23 (d, J=8.4 Hz, 1H), 7.04 (d, J=8.4 Hz, 1H), 6.16 (s, 2H).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08653263B2 |
| 출처 데이터셋 | uspto-grants-2014_02 |
| ORD ID | ord-b341898934e34a8893c5ce2a657c19dc |
| 출처 메모 | uspto-grants-2014_02 |