반응식
[C:1]1([C:7]2[CH:12]=[CH:11][N:10]=[C:9]([N:13]3[CH2:20][CH:19]4[CH:15]([CH2:16][NH:17][CH2:18]4)[CH2:14]3)[N:8]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[F:21][C:22]1[CH:23]=[CH:24][C:25]([C:31]2[N:36]=[CH:35][CH:34]=[CH:33][N:32]=2)=[C:26]([CH:30]=1)[C:27](O)=[O:28]>>[F:21][C:22]1[CH:23]=[CH:24][C:25]([C:31]2[N:32]=[CH:33][CH:34]=[CH:35][N:36]=2)=[C:26]([C:27]([N:17]2[CH2:16][CH:15]3[CH:19]([CH2:20][N:13]([C:9]4[N:8]=[C:7]([C:1]5[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=5)[CH:12]=[CH:11][N:10]=4)[CH2:14]3)[CH2:18]2)=[O:28])[CH:30]=1참가 물질
3
실험 절차
The title compound was prepared in a manner analogous to Example 15 utilizing Intermediate 26 and Intermediate 13. MS (ESI): mass calculated for C27H23FN6O, 466.52; m/z found 467.2 [M+H]+. 1H NMR (400 MHz, CDCl3): 8.72-8.66 (m, 2H), 8.44-8.29 (m, 2H), 8.16-8.02 (m, 2H), 7.53-7.45 (m, 3H), 7.21-7.14 (m, 1H), 7.10-7.06 (m, 1H), 7.01-6.98 (m, 1H), 6.87 (br s, 1H), 4.05-3.50 (m, 7H), 3.31-2.98 (m, 3H).
출처 및 근거
- ORD 기록
- ord-bd3657c26fb94ce3b7eca2f894b084a5
- 출처 데이터셋
- uspto-grants-2014_02
- 특허 번호
- US08653263B2
연결된 노트
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