2-Chloro-6-methoxybenzothiazole → Biphenyl-2-yl-[5-(6-methoxy-benzothiazol-2-yl)-hexahydro-pyrrolo[3,4-c]pyrrol-2-yl]-methanone
반응식
[C:1]1([C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[C:7]([N:9]1[CH2:16][CH:15]2[CH:11]([CH2:12][NH:13][CH2:14]2)[CH2:10]1)=[O:8].Cl[C:24]1[S:25][C:26]2[CH:32]=[C:31]([O:33][CH3:34])[CH:30]=[CH:29][C:27]=2[N:28]=1>>[C:1]1([C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[C:7]([N:9]1[CH2:10][CH:11]2[CH:15]([CH2:14][N:13]([C:24]3[S:25][C:26]4[CH:32]=[C:31]([O:33][CH3:34])[CH:30]=[CH:29][C:27]=4[N:28]=3)[CH2:12]2)[CH2:16]1)=[O:8]참가 물질
3
실험 절차
The title compound was prepared in a manner analogous to Example 15 utilizing Intermediate 17 and 2-chloro-6-methoxy-benzothiazole. MS (ESI): mass calculated for C27H25N3O2S, 455.57; m/z found 456.2 [M+H]+.
출처 및 근거
- ORD 기록
- ord-f0b717bc488d4683ac5650f22343c4af
- 출처 데이터셋
- uspto-grants-2014_02