4'-(Trifluoromethyl)(1,1'-biphenyl)-2-carboxylic acid → HCID 67116489, 화합물

HRID 243998

반응식

HRID 243998 반응식
[CH2:1]1[CH:5]2[CH2:6][NH:7][CH2:8][CH:4]2[CH2:3][N:2]1[C:9]1[CH:18]=[N:17][C:16]2[C:11](=[CH:12][CH:13]=[CH:14][CH:15]=2)[N:10]=1.[F:19][C:20]([F:37])([F:36])[C:21]1[CH:26]=[CH:25][C:24]([C:27]2[C:28]([C:33](O)=[O:34])=[CH:29][CH:30]=[CH:31][CH:32]=2)=[CH:23][CH:22]=1>>[N:10]1[C:11]2[C:16](=[CH:15][CH:14]=[CH:13][CH:12]=2)[N:17]=[CH:18][C:9]=1[N:2]1[CH2:3][CH:4]2[CH2:8][N:7]([C:33]([C:28]3[CH:29]=[CH:30][CH:31]=[CH:32][C:27]=3[C:24]3[CH:25]=[CH:26][C:21]([C:20]([F:19])([F:36])[F:37])=[CH:22][CH:23]=3)=[O:34])[CH2:6][CH:5]2[CH2:1]1

참가 물질

3

반응물 2

HCID 552514'-(Trifluoromethyl)(1,1'-biphenyl)-2-carboxylic acidHCID 610372812-(Hexahydro-pyrrolo[3,4-c]pyrrol-2-yl)-quinoxaline

생성물 1

HCID 67116489HCID 67116489, 화합물

실험 절차

The title compound was prepared in a manner analogous to Example 15 utilizing Intermediate 35 and 4′-trifluoromethyl-biphenyl-2-carboxylic acid. MS (ESI): mass calculated for C28H23F3N4O, 488.50; m/z found 489.2 [M+H]+.

출처 및 근거

ORD 기록
ord-852d7d83eecb4d8cad3ec3a95baa068e
출처 데이터셋
uspto-grants-2014_02
특허 번호
US08653263B2

연결된 노트

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