Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3-Fluoro-2-(2H-1,2,3-triazol-2-yl)benzoic acid → HCID 67116820, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3-Fluoro-2-(2H-1,2,3-triazol-2-yl)benzoic acid | HCID 67086549 | — |
| 반응물 | 6-Fluoro-2-(hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl)quinazoline | HCID 69939155 | — |
| 생성물 | HCID 67116820 | HCID 67116820 | — |
반응 단계
The title compound was prepared in a manner analogous to Example 15, utilizing Intermediate 43 and 3-fluoro-2-(2H-1,2,3-triazol-2-yl)benzoic acid. MS (ESI): mass calculated for C23H19F2N7O, 447.16; m/z found 448.1 [M+H]+. 1H NMR (500 MHz, CDCl3): 8.99 (s, 1H), 7.77 (d, J=15.8, 2H), 7.61 (dd, J=11.0, 5.5, 1H), 7.53-7.43 (m, 2H), 7.37-7.29 (m, 2H), 7.24 (s, 1H), 3.93 (d, J=9.9, 1H), 3.79 (dd, J=12.3, 7.4, 2H), 3.71-3.62 (m, 1H), 3.62 (s, 3H), 3.20 (dd, J=11.0, 5.3, 1H), 3.12-2.98 (m, 2H).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08653263B2 |
| 출처 데이터셋 | uspto-grants-2014_02 |
| ORD ID | ord-be716e9f2aae458688f3a4162f3766ba |
| 출처 메모 | uspto-grants-2014_02 |