돌아가기
Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 244026생성일: 2026년 10월 26일

2-Methoxy-4-methylbenzoic acid → (5-(4,6-Dimethylpyrimidin-2-yl)hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl)(2-methoxy-4-methylphenyl)methanone

https://huagongshe.com/reaction/244026

반응식

참여 물질

역할이름HCID투입량
반응물2-Methoxy-4-methylbenzoic acidHCID 597164—
반응물2-(4,6-Dimethylpyrimidin-2-yl)octahydropyrrolo[3,4-c]pyrroleHCID 66210875—
생성물(5-(4,6-Dimethylpyrimidin-2-yl)hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl)(2-methoxy-4-methylphenyl)methanoneHCID 67116335—

반응 단계

The title compound was prepared in a manner analogous to Example 15, utilizing Intermediate 23 and 2-methoxy-4-methylbenzoic acid. MS (ESI): mass calculated for C21H26N4O2, 366.21; m/z found 367.3 [M+H]+. 1H NMR (400 MHz, CDCl3): 7.13 (d, J=7.6, 1H), 6.77 (d, J=7.6, 1H), 6.70 (s, 1H), 6.28 (s, 1H), 4.00-3.40 (m, 11H), 3.27-2.85 (m, 3H), 2.41-2.19 (m, 9H).

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US08653263B2
출처 데이터셋uspto-grants-2014_02
ORD IDord-4948e3e8218a4275b4791c32582e17e3
출처 메모uspto-grants-2014_02