Oxindole → 3-(2,3-Dihydrobenzofuran-5-ylmethylene)-1,3-dihydroindol-2-one

반응식

[CH:1]([C:3]1[CH:4]=[CH:5][C:6]2[O:10][CH2:9][CH2:8][C:7]=2[CH:11]=1)=O.[NH:12]1[C:20]2[C:15](=[CH:16][CH:17]=[CH:18][CH:19]=2)[CH2:14][C:13]1=[O:21]>>[O:10]1[C:6]2[CH:5]=[CH:4][C:3]([CH:1]=[C:14]3[C:15]4[C:20](=[CH:19][CH:18]=[CH:17][CH:16]=4)[NH:12][C:13]3=[O:21])=[CH:11][C:7]=2[CH2:8][CH2:9]1

참가 물질

반응물 2

HCID 321710Oxindole

HCID 7359012,3-Dihydrobenzofuran-5-carboxaldehyde

생성물 1

HCID 27386933-(2,3-Dihydrobenzofuran-5-ylmethylene)-1,3-dihydroindol-2-one

실험 절차

2,3-Dihydro-5-formylbenzofuran (commercially available) was condensed with 2-oxindole to give 0.25 g of 3-(2,3-dihydrobenzofuran-5-ylmethylene)-1,3-dihydroindol-2-one as a yellow-orange solid.

출처 및 근거

ORD 기록: ord-3b4b55e0eb604ecb8ab83ad3bb05ddd0
출처 데이터셋: uspto-grants-2005_02
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US06855730B2

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