5-bromo-1-(4-fluorophenyl)-1H-indazole → 1-allyl-4-{2,2,2-trifluoro-1-[1-(4-fluorophenyl)-1H-indazol-5-yl]-1-hydroxyethyl}-1H-pyrrole-2-carboxylic acid ethyl ester

반응식

Br[C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[N:7]([C:11]1[CH:16]=[CH:15][C:14]([F:17])=[CH:13][CH:12]=1)[N:6]=[CH:5]2.[Li]CCCC.[CH2:23]([O:25][C:26]([C:28]1[N:29]([CH2:39][CH:40]=[CH2:41])[CH:30]=[C:31]([C:33](=[O:38])[C:34]([F:37])([F:36])[F:35])[CH:32]=1)=[O:27])[CH3:24]>C1COCC1>[CH2:23]([O:25][C:26]([C:28]1[N:29]([CH2:39][CH:40]=[CH2:41])[CH:30]=[C:31]([C:33]([C:2]2[CH:3]=[C:4]3[C:8](=[CH:9][CH:10]=2)[N:7]([C:11]2[CH:16]=[CH:15][C:14]([F:17])=[CH:13][CH:12]=2)[N:6]=[CH:5]3)([OH:38])[C:34]([F:36])([F:35])[F:37])[CH:32]=1)=[O:27])[CH3:24]