Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Piperidine → 5-methyl-3-(3-methyl-1H-indol-2-ylmethylene)-1,3-dihydroindol-2-one
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Piperidine | HCID 8082 | — |
| 반응물 | 3-Methyl-1H-indole-2-carbaldehyde | HCID 277260 | — |
| 반응물 | 5-Methylindolin-2-one | HCID 5325716 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | 5-methyl-3-(3-methyl-1H-indol-2-ylmethylene)-1,3-dihydroindol-2-one | HCID 53755378 | 74% |
반응 단계
A mixture of 5-methyl-2-oxindole (59 mg), 3-methylindole-2-carbaldehyde (56 mg) and piperidine (30 mg) in ethanol(1 mL) was held in a sealed tube at 90° C. overnight. The mixture was cooled to room temperature. The solid was collected by vacuum filtration, washed with cold ethanol and dried in a vacuum oven to give 72 mg (74%) of 5-methyl-3-(3-methyl-1H-indol-2-ylmethylene)-1,3-dihydroindol-2-one.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06855730B2 |
| 출처 데이터셋 | uspto-grants-2005_02 |
| ORD ID | ord-6971769eafbc44aa928743994cee0fcd |
| 출처 메모 | uspto-grants-2005_02 |