Dimethyldioxirane → 8-Benzyloxy-3-methyl5-oxiranyl-1H-quinolin-2-one

HRID 244770

반응식

HRID 244770 반응식
[CH2:1]([O:8][C:9]1[CH:10]=[CH:11][C:12]([CH:21]=[CH2:22])=[C:13]2[C:18]=1[NH:17][C:16](=[O:19])[C:15]([CH3:20])=[CH:14]2)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.CC1(C)O[O:25]1>CC(C)=O>[CH2:1]([O:8][C:9]1[CH:10]=[CH:11][C:12]([CH:21]2[CH2:22][O:25]2)=[C:13]2[C:18]=1[NH:17][C:16](=[O:19])[C:15]([CH3:20])=[CH:14]2)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

참가 물질

4

반응물 2

HCID 115197DimethyldioxiraneHCID 224991788-Benzyloxy-3-methyl-5-vinyl-1H-quinolin-2-one

생성물 1

HCID 574942318-Benzyloxy-3-methyl5-oxiranyl-1H-quinolin-2-one

시약·촉매·용매 1

HCID 180Acetone용매

실험 절차

To 8-benzyloxy-3-methyl-5-vinyl-1H-quinolin-2-one (300 mg) is added to a 0.1M solution of dimethyldioxirane in acetone (12.4 mL). After stirring at room temperature for 2 hours, the solvent is removed in vacuo to yield the product.

후처리

  1. customthe solvent is removed in vacuo
  2. customto yield the product

출처 및 근거

ORD 기록
ord-024d87e41e5148058d65a29ff234a912
출처 데이터셋
uspto-grants-2014_02
특허 번호
US08658673B2

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