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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 245398생성일: 2026년 10월 25일

2-Methyl-1,3-thiazole-5-carbaldehyde → (6-((tert-butyldiphenylsilyloxy)methyl)-4-chloro-5-((2R,6S)-2,6-dimethylmorpholino)-3-fluoropyridin-2-yl)(2-methylthiazol-5-yl)methanol

https://huagongshe.com/reaction/245398

반응식

참여 물질

역할이름HCID투입량
반응물2-Methyl-1,3-thiazole-5-carbaldehydeHCID 13934728—
반응물(2R,6S)-4-(2-((tert-Butyldiphenylsilyloxy)methyl)-4-chloro-5-fluoropyridin-3-yl)-2,6-dimethylmorpholineHCID 67319975—
생성물(6-((tert-butyldiphenylsilyloxy)methyl)-4-chloro-5-((2R,6S)-2,6-dimethylmorpholino)-3-fluoropyridin-2-yl)(2-methylthiazol-5-yl)methanolHCID 67356845—

반응 단계

Starting materials: (2R,6S)-4-(2-((tert-butyldiphenylsilyloxy)methyl)-4-chloro-5-fluoropyridin-3-yl)-2,6-dimethylmorpholine (Intermediate 45) and 2-methylthiazole-5-carbaldehyde.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US08658641B2
출처 데이터셋uspto-grants-2014_02
ORD IDord-312a485e7b1a4d32bcdb52bf6f313d3f
출처 메모uspto-grants-2014_02