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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 245419생성일: 2026년 10월 26일

N-Methoxy-6,N-dimethyl-nicotinamide → (5-((tert-butyldiphenylsilyloxy)methyl)-4-((2R,6S)-2,6-dimethylmorpholino)-2,3-difluorophenyl)(6-methylpyridin-3-yl)methanone

https://huagongshe.com/reaction/245419

반응식

참여 물질

역할이름HCID투입량
반응물N-Methoxy-6,N-dimethyl-nicotinamideHCID 11367353—
반응물(2R,6S)-4-(6-((tert-butyldiphenylsilyloxy)methyl)-2,3-difluorophenyl)-2,6-dimethylmorpholineHCID 67357593—
생성물(5-((tert-butyldiphenylsilyloxy)methyl)-4-((2R,6S)-2,6-dimethylmorpholino)-2,3-difluorophenyl)(6-methylpyridin-3-yl)methanoneHCID 86658073—

반응 단계

Starting materials (2R,6S)-4-(6-((tert-butyldiphenylsilyloxy)methyl)-2,3-difluorophenyl)-2,6-dimethylmorpholine (Intermediate 3 and N-methoxy-N, 6-dimethylnicotinamide.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US08658641B2
출처 데이터셋uspto-grants-2014_02
ORD IDord-de96b4d30b2642ff99e5890b98f68f5b
출처 메모uspto-grants-2014_02