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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 245432생성일: 2026년 10월 26일

N-Methoxy-N-methylpyrazine-2-carboxamide → (6-((tert-butyldiphenylsilyloxy)methyl)-4-chloro-5-((2R,6S)-2,6-dimethylmorpholino)-3-fluoropyridin-2-yl)(pyrazin-2-yl)methanone

https://huagongshe.com/reaction/245432

반응식

참여 물질

역할이름HCID투입량
반응물N-Methoxy-N-methylpyrazine-2-carboxamideHCID 22613131—
반응물(2R,6S)-4-(2-((tert-Butyldiphenylsilyloxy)methyl)-4-chloro-5-fluoropyridin-3-yl)-2,6-dimethylmorpholineHCID 67319975—
생성물(6-((tert-butyldiphenylsilyloxy)methyl)-4-chloro-5-((2R,6S)-2,6-dimethylmorpholino)-3-fluoropyridin-2-yl)(pyrazin-2-yl)methanoneHCID 67356590—

반응 단계

Starting material: (2-((tert-butyldiphenylsilyloxy)methyl)-4-chloro-5-fluoropyridin-3-yl)-2,6-dimethylmorpholine (Intermediate 45) and N-methoxy-N-methylpyrazine-2-carboxamide.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US08658641B2
출처 데이터셋uspto-grants-2014_02
ORD IDord-cb2c2bc3ac0446ea8395fcbe7f975b6b
출처 메모uspto-grants-2014_02