Isopropylamine → 5-(dimethoxymethyl)-6,7-difluoro-N-isopropylbenzo[d]isoxazole-3-carboxamide

HRID 245474노트

반응식

HRID 245474 반응식
[CH3:1][O:2][CH:3]([O:20][CH3:21])[C:4]1[C:5]([F:19])=[C:6]([F:18])[C:7]2[O:11][N:10]=[C:9]([C:12]([O:14]CC)=O)[C:8]=2[CH:17]=1.[CH:22]([NH2:25])([CH3:24])[CH3:23]>>[CH3:21][O:20][CH:3]([O:2][CH3:1])[C:4]1[C:5]([F:19])=[C:6]([F:18])[C:7]2[O:11][N:10]=[C:9]([C:12]([NH:25][CH:22]([CH3:24])[CH3:23])=[O:14])[C:8]=2[CH:17]=1

참가 물질

3

반응물 2

HCID 6363IsopropylamineHCID 67360293Ethyl 5-(dimethoxymethyl)-6,7-difluorobenzo[d]isoxazole-3-carboxylate2회

생성물 1

HCID 673568315-(dimethoxymethyl)-6,7-difluoro-N-isopropylbenzo[d]isoxazole-3-carboxamide

실험 절차

Starting materials: ethyl 5-(dimethoxymethyl)-6,7-difluorobenzo[d]isoxazole-3-carboxylate (Intermediate 206) and isopropyl amine.

출처 및 근거

ORD 기록
ord-2ab8f060f7b24ea5901e4eb180bf0857
출처 데이터셋
uspto-grants-2014_02
특허 번호
US08658641B2

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