trans-2,6-Dimethylmorpholine → HCID 86658124, 화합물

HRID 245534노트

반응식

HRID 245534 반응식
F[C:2]1[C:16]([CH:17]=[O:18])=[CH:15][C:5]2[C:6]([C:9]3[N:13]([CH3:14])[N:12]=[CH:11][N:10]=3)=[N:7][O:8][C:4]=2[C:3]=1[F:19].[CH3:20][C@H:21]1[O:26][C@H:25]([CH3:27])[CH2:24][NH:23][CH2:22]1>>[CH3:27][C@@H:25]1[CH2:24][N:23]([C:2]2[C:16]([CH:17]=[O:18])=[CH:15][C:5]3[C:6]([C:9]4[N:13]([CH3:14])[N:12]=[CH:11][N:10]=4)=[N:7][O:8][C:4]=3[C:3]=2[F:19])[CH2:22][C@@H:21]([CH3:20])[O:26]1

참가 물질

3

반응물 2

HCID 11137133trans-2,6-DimethylmorpholineHCID 86658125HCID 86658125, 화합물2회

생성물 1

HCID 86658124HCID 86658124, 화합물

실험 절차

Starting materials: 6,7-difluoro-3-(1-methyl-1H-1,2,4-triazol-5-yl)benzo[d]isoxazole-5-carbaldehyde (Intermediate 404) and (2R,6R)-2,6-dimethylmorpholine.

출처 및 근거

ORD 기록
ord-aa1a48081e64426faf2baef31f99b9a1
출처 데이터셋
uspto-grants-2014_02
특허 번호
US08658641B2

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