Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Ethyl 3-(bromophenyl)acetate → Ethyl 4-(3-bromophenyl)butanoate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Ethyl 3-(bromophenyl)acetate | HCID 11470552 | — |
| 반응물 | Ethyl 4-(4-bromophenyl)butanoate | HCID 12870375 | — |
| 생성물 | Ethyl 4-(3-bromophenyl)butanoate | HCID 11492759 | — |
반응 단계
Employing the same general multistep preparation as for ethyl 4-(4-bromophenyl)butanoate (Compound C), 60 g (246 mmol) of ethyl (3-bromophenyl)acetate (Compound B) was converted into the title compound (oil) using 255 ml (255 mmol) of diisobutylaluminum hydride (DIBAl—H, 1M in hexane), 85.8 g (250 mmol) of (carbethoxymethylene)triphenylphosphorane and 1.7 g of 10% Pd/C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06855832B2 |
| 출처 데이터셋 | uspto-grants-2005_02 |
| ORD ID | ord-bc40a9034acc40c2b93dfccab2c8cce2 |
| 출처 메모 | uspto-grants-2005_02 |